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Perspective needed on HHS Flu Vaccine Allocation Plan

Posted on Thursday, October 25, 2007 at 01:02PM by Registered CommenterScott McPherson in , | Comments3 Comments

ElephantintheRoom.jpg

The news media (to the extent they are not covering Britney Spears' underwear, marital problems or inbibing habits) have generated many stories regarding the recent release of the draft HHS vaccine distribution guidelines.

It is my pleasure to now talk about The Elephant In The Room that everyone has so convenienty neglected. 

This follows a telephone interview with Computerworld's Patrick Thibodeau.  Pat is one of the few reporters who habitually reports on avian influenza and its potential pandemic effect on the information technology sector.  Pat rang me up to get my opinion of the draft HHS vaccine guidelines.  Where does IT fit on the tiered ladder?  How would an organization determine where it is in the pecking order (sorry) for vaccine?

After breaking down the draft guidelines, I then spoke of that danged elephant.  It is a message that bears repeating over, and over, and over again.

A vaccine -- ANY vaccine, save possibly the prepandemic goulash that is cooking in (far too many) labs across the world -- will not be in your arm for at least six to eight months following the start of an influenza pandemic.  That is Wave Two, maybe even Wave Three of the pandemic, since we have no idea whatsoever how many waves the Next Pandemic will be, or how long it will take each wave to travel.  Even that six to eight month vaccine timeframe is for Tier A and B receipents.  Forget about the general public.  Vaccine will be trickling out with agonizing slowness. 

We also do not know if the virus will be moderate or severe (the report says in a light to moderate pandemic, don't even sweat the vaccine).  And we don't know if, like 1918, the second wave will be the killer.  Recall it was the third wave in 1919 that felled President Woodrow Wilson at the most sensitive stage of the armistice talks and, ultimately, set the stage for the Third Reich.    And remember that in 1976, with far more manufacturers and a Get Out of Court Free vaccine boo-boo cards courtesy of the Congress, they still had to throw out millions of doses of vaccine because the virus drifted during the manufacturing process.  There is no guarantee the same thing won't happen again.  Heck, it happens routinely today. 

So any organization that is seriously concerned about its place in the pecking order for vaccine is decidedly missing the point.  That point is that there will be a six to eight month window of incredible suffering, lost wages, declining economic news, hunger -- and death -- for many months prior to the availibility of vaccine.  That means organizations need to focus NOW on such basic things as hand sanitizer, gloves and masks.  They need to focus on Tamiflu if they can get it, but if they can't, then they need to focus elsewhere.  All need to focus on the things that Momma taught us -- hand washing, personal hygiene, and keeping a respectable distance from strangers.

koop.jpgThe report is available as a PDF file from www.pandemicflu,gov, specifically at the following location: http://pandemicflu.gov/vaccine/prioritization.pdf .

I close with the recent words of former Surgeon General C. Everett Koop, who said: "We're fighting today's pandemic with the same tools we had one hundred years ago." 

Take those words to heart and prepare for what you can do today.

Reader Comments (3)

Very good points. You may want to take a look at a project that we have just started rolling out at CIDRAP, "The Pandemic Vaccine Puzzle," that addresses these issues. It is a 7-part series that explores panflu vaccine research and policy and will closely examine funding, manufacturing capacity, research agenda and lots more. Link to the first installment (sorry, can't see how to make this a live link):
http://www.cidrap.umn.edu/cidrap/content/influenza/panflu/news/oct2507panvax1.html

October 25, 2007 | Unregistered Commentermaryn

The elephant is right there in front of us. A point to be made is that once H5N1 has done its damage waves 1,2, and 3 with the majority of persons vulnerable having been infected, it now lies within the influenza gene pool of human yearly "garden variety" flu. I am no expert, but have read sources stating that the "common" yearly influenza in the decade following the 1918 pandemic was much more severe than it had been previously. So, after our 6-8 months of wait to get the shot, if our current civilization stands to the extent that it offers us any vaccines, we do ourselves benefit to get flu shots yearly to avoid the second worst flu we ever may have in our lives.

October 26, 2007 | Unregistered CommenterBugust

Bugust,
A very good point. I will look at the mortality charts follwoing 1818-19 to see what happened. It is quite reasonable to expect significantly higher mortality in the immediate aftermath of a pandemic. There have been pandemics in the past where the aftershock was worse than the pandemic itself. I just cannot recall which ones they were.

I myself get two flu shots from different manufacturers each season, spaced about six to eight weeks apart. My theory is that the virus "drifts" slightly during the manufacturing process anyway; so getting two vaccines, from two different manufacturers, in theory protects against any "drifts" from the target strains. In theory, anyway. So far, so good.

October 29, 2007 | Registered CommenterScott McPherson

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